Antiplatelet and Anticoagulation   
The benefits and risks of abciximab, eptifibatide, or tirofiban during PCI: class effects or do they differ
Catheter Cardiovasc Interv (2009) 73; 222-3
F. Zijlstra
Randomized trial comparing 600- with 300-mg loading dose of clopidogrel in patients with non-ST elevation acute coronary syndrome undergoing percutaneous coronary intervention: results of the Platelet Responsiveness to Aspirin and Clopidogrel and Troponin Increment after Coronary intervention in Acute coronary Lesions (PRACTICAL) Trial
Am Heart J (2009) 157; 60 e1-9
. Yong, J. Rankin, L. Ferguson, J. Thom, J. French, D. Brieger, D. P. Chew, R. Dick, D. Eccleston, B. Hockings, D. Walters, A. Whelan and J. W. Eikelboom
Anticoagulation with the direct thrombin inhibitor argatroban in patients presenting with acute coronary syndromes
Catheter Cardiovasc Interv (2009)
. W. Yeh, S. J. Baron, J. L. Healy, E. Pomerantsev, I. A. McNulty, I. Cruz-Gonzalez and I. K. Jang
Determinants of thrombin generation, fibrinolytic activity, and endothelial dysfunction in patients on dual antiplatelet therapy: involvement of factors other than platelet aggregability in Virchow's triad
Eur Heart J (2008) 29; 1729-38
Y. Yano, T. Ohmori, S. Hoshide, S. Madoiwa, K. Yamamoto, T. Katsuki, T. Mitsuhashi, J. Mimuro, K. Shimada, K. Kario and Y. Sakata
Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: a subanalysis of a randomised trial
Lancet (2008) 371; 1353-63
S. D. Wiviott, E. Braunwald, C. H. McCabe, I. Horvath, M. Keltai, J. P. Herrman, F. Van de Werf, W. E. Downey, B. M. Scirica, S. A. Murphy and E. M. Antman
Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-Thrombolysis in Myocardial Infarction 38
Circulation (2008) 118; 1626-36
S. D. Wiviott, E. Braunwald, D. J. Angiolillo, S. Meisel, A. J. Dalby, F. W. Verheugt, S. G. Goodman, R. Corbalan, D. A. Purdy, S. A. Murphy, C. H. McCabe and E. M. Antman
Safety and efficacy of bivalirudin with and without glycoprotein IIb/IIIa inhibitors in patients with acute coronary syndromes undergoing percutaneous coronary intervention 1-year results from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial
J Am Coll Cardiol (2008) 52; 807-14
H. D. White, E. M. Ohman, A. M. Lincoff, M. E. Bertrand, A. Colombo, B. T. McLaurin, D. A. Cox, S. J. Pocock, J. A. Ware, S. V. Manoukian, A. J. Lansky, R. Mehran, J. W. Moses and G. W. Stone
The use of intravenous enoxaparin in elective percutaneous coronary intervention in patients with renal impairment: results from the SafeTy and Efficacy of Enoxaparin in PCI patients, an internationaL randomized Evaluation (STEEPLE) trial
Am Heart J (2009) 157; 125-31
H. D. White, R. Gallo, M. Cohen, P. G. Steg, P. E. Aylward, C. Bode, S. Steinhubl and G. Montalescot
Safety and efficacy of switching from either unfractionated heparin or enoxaparin to bivalirudin in patients with non-ST-segment elevation acute coronary syndromes managed with an invasive strategy: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial
J Am Coll Cardiol (2008) 51; 1734-41
H. D. White, D. P. Chew, J. W. Hoekstra, C. D. Miller, C. V. Pollack, Jr., F. Feit, A. M. Lincoff, M. Bertrand, S. Pocock, J. Ware, E. M. Ohman, R. Mehran and G. W. Stone
Discharge antithrombotic strategies among patients with acute coronary syndrome previously on warfarin anticoagulation: physician practice in the CRUSADE registry
Am Heart J (2008) 155; 361-8
T. Y. Wang, L. A. Robinson, F. S. Ou, M. T. Roe, E. M. Ohman, W. B. Gibler, S. C. Smith, Jr., E. D. Peterson and R. C. Becker
Impact of home warfarin use on treatment patterns and bleeding complications for patients with non-ST-segment elevation acute coronary syndromes: observations from the CRUSADE quality improvement initiative
Eur Heart J (2008) 29; 1103-9
T. Y. Wang, A. Y. Chen, E. D. Peterson, R. C. Becker, W. B. Gibler, E. M. Ohman and M. T. Roe
Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease
Eur Heart J (2008) 29; 21-30
L. Wallentin, C. Varenhorst, S. James, D. Erlinge, O. O. Braun, J. A. Jakubowski, A. Sugidachi, K. J. Winters and A. Siegbahn
Prasugrel versus clopidogrel
N Engl J Med (2008) 358; 1299; author reply 99-301
F. von Lewinski, J. Riggert and W. Paulus
Cardiac death and reinfarction after 1 year in the Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction Study (TAPAS): a 1-year follow-up study
Lancet (2008) 371; 1915-20
P. J. Vlaar, T. Svilaas, I. C. van der Horst, G. F. Diercks, M. L. Fokkema, B. J. de Smet, A. F. van den Heuvel, R. L. Anthonio, G. A. Jessurun, E. S. Tan, A. J. Suurmeijer and F. Zijlstra
Impact of pretreatment with clopidogrel on initial patency and outcome in patients treated with primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: a systematic review
Circulation (2008) 118; 1828-36
P. J. Vlaar, T. Svilaas, K. Damman, B. J. de Smet, J. G. Tijssen, H. L. Hillege and F. Zijlstra
Assessment of P2Y(12) inhibition with the point-of-care device VerifyNow P2Y12 in patients treated with prasugrel or clopidogrel coadministered with aspirin
Am Heart J (2009) 157; 562 e1-9
C. Varenhorst, S. James, D. Erlinge, O. O. Braun, J. T. Brandt, K. J. Winters, J. A. Jakubowski, S. Olofsson, L. Wallentin and A. Siegbahn
Prehospital initiation of tirofiban in patients with ST-elevation myocardial infarction undergoing primary angioplasty (On-TIME 2): a multicentre, double-blind, randomised controlled trial
Lancet (2008) 372; 537-46
A. W. Van't Hof, J. Ten Berg, T. Heestermans, T. Dill, R. C. Funck, W. van Werkum, J. H. Dambrink, H. Suryapranata, G. van Houwelingen, J. P. Ottervanger, P. Stella, E. Giannitsis and C. Hamm
Prolonged anticoagulation therapy adjunctive to aspirin after successful fibrinolysis: from early reduction in reocclusion to improved long-term clinical outcome
Am Heart J (2009) 157; 532-40
P. J. van den Bergh, P. C. Kievit, M. A. Brouwer, W. R. Aengevaeren, G. Veen and F. W. Verheugt
Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents
J Am Coll Cardiol (2008) 51; 1925-34
D. Trenk, W. Hochholzer, M. F. Fromm, L. E. Chialda, A. Pahl, C. M. Valina, C. Stratz, P. Schmiebusch, H. P. Bestehorn, H. J. Buttner and F. J. Neumann
Intracoronary compared with intravenous bolus abciximab application in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: the randomized Leipzig immediate percutaneous coronary intervention abciximab IV versus IC in ST-elevation myocardial infarction trial
Circulation (2008) 118; 49-57
H. Thiele, K. Schindler, J. Friedenberger, I. Eitel, G. Furnau, E. Grebe, S. Erbs, A. Linke, S. Mobius-Winkler, D. Kivelitz and G. Schuler
Temporal course of pregnancy-associated plasma protein-A in angioplasty-treated ST-elevation myocardial infarction patients and potential significance of concomitant heparin administration
Am J Cardiol (2009) 103; 29-35
C. J. Terkelsen, C. Oxvig, B. L. Norgaard, S. Glerup, T. S. Poulsen, J. F. Lassen, H. J. Moller, L. Thuesen, E. Falk, T. T. Nielsen and H. R. Andersen
Left ventricular function after ST-elevation myocardial infarction in patients treated with primary percutaneous coronary intervention and abciximab or tirofiban (from the Facilitated Angioplasty with Tirofiban or Abciximab [FATA] Trial)
Am J Cardiol (2009) 103; 785-90
N. Taglieri, F. Saia, V. Guiducci, S. Tondi, F. Conrotto, C. Marrozzini, G. Rocchi, E. Biagini, M. L. Reggiani, P. Giacometti, G. Piovaccari, A. Manari and A. Marzocchi
Clopidogrel in acute coronary syndrome: to genotype or not?
Lancet (2009) 373; 276-8
R. F. Storey
Bivalirudin during primary PCI in acute myocardial infarction
N Engl J Med (2008) 358; 2218-30
G. W. Stone, B. Witzenbichler, G. Guagliumi, J. Z. Peruga, B. R. Brodie, D. Dudek, R. Kornowski, F. Hartmann, B. J. Gersh, S. J. Pocock, G. Dangas, S. C. Wong, A. J. Kirtane, H. Parise and R. Mehran
Aspirin following PCI: too much of a good thing
Eur Heart J (2009)
S. R. Steinhubl and P. B. Berger
The CIAO (Coronary Interventions Antiplatelet-based Only) Study: a randomized study comparing standard anticoagulation regimen to absence of anticoagulation for elective percutaneous coronary intervention
J Am Coll Cardiol (2008) 52; 1293-8
E. Stabile, W. Nammas, L. Salemme, G. Sorropago, A. Cioppa, T. Tesorio, V. Ambrosini, E. Campopiano, G. Popusoi, G. Biondi Zoccai and P. Rubino
Genetic determinants of response to clopidogrel and cardiovascular events
N Engl J Med (2009) 360; 363-75
T. Simon, C. Verstuyft, M. Mary-Krause, L. Quteineh, E. Drouet, N. Meneveau, P. G. Steg, J. Ferrieres, N. Danchin and L. Becquemont
Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel
Am Heart J (2009) 157; 148 e1-5
. M. Siller-Matula, A. O. Spiel, I. M. Lang, G. Kreiner, G. Christ and B. Jilma
Calcium-channel blockers reduce the antiplatelet effect of clopidogrel
J Am Coll Cardiol (2008) 52; 1557-63
J. M. Siller-Matula, I. Lang, G. Christ and B. Jilma
Impact of bivalirudin or unfractionated heparin on platelet aggregation in patients pretreated with 600 mg clopidogrel undergoing elective percutaneous coronary intervention
Eur Heart J (2008) 29; 1504-9
D. Sibbing, G. Busch, S. Braun, S. Jawansky, A. Schomig, A. Kastrati, I. Ott and N. von Beckerath
Platelet reactivity after clopidogrel treatment assessed with point-of-care analysis and early drug-eluting stent thrombosis
J Am Coll Cardiol (2009) 53; 849-56
D. Sibbing, S. Braun, T. Morath, J. Mehilli, W. Vogt, A. Schomig, A. Kastrati and N. von Beckerath
Multiple mechanisms affect the clopidogrel response
J Am Coll Cardiol (2009) 53; 900-1; author reply 01
G. Siasos, D. Tousoulis and C. Stefanadis
Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease
Am J Cardiol (2008) 101; 1741-6
M. H. Shishehbor, L. P. Oliveira, M. S. Lauer, D. L. Sprecher, K. Wolski, L. Cho, B. J. Hoogwerf and S. L. Hazen
Effects of clopidogrel and aspirin in combination versus aspirin alone on platelet activation and major receptor expression in diabetic patients: the PLavix Use for Treatment Of Diabetes (PLUTO-Diabetes) trial
Am Heart J (2008) 155; 93 e1-7
V. L. Serebruany, A. I. Malinin, A. Pokov, G. Barsness and D. F. Hanley
The challenge of monitoring platelet response after clopidogrel
Eur Heart J (2008) 29; 2833-4
V. L. Serebruany and S. Goto
Prasugrel versus clopidogrel
N Engl J Med (2008) 358; 1298; author reply 99-301
V. Serebruany
The ELAPSE (Evaluation of Long-Term Clopidogrel Antiplatelet and Systemic Anti-Inflammatory Effects) study
J Am Coll Cardiol (2008) 52; 1826-33
J. Saw, E. H. Madsen, S. Chan and E. Maurer-Spurej
Efficacy and safety of clopidogrel pretreatment before percutaneous coronary intervention with and without glycoprotein IIb/IIIa inhibitor use
Am Heart J (2008) 155; 910-7
M. S. Sabatine, H. N. Hamdalla, S. R. Mehta, K. A. Fox, E. J. Topol, S. R. Steinhubl and C. P. Cannon
Which patients receiving warfarin can be treated safely with a drug-eluting stent?
Heart (2008) 94; 275-7
A. D. Ryding and A. P. Banning
Long-term outcomes in patients undergoing coronary stenting on dual oral antiplatelet treatment requiring oral anticoagulant therapy
Am J Cardiol (2008) 102; 1618-23
R. Rossini, G. Musumeci, C. Lettieri, M. Molfese, L. Mihalcsik, P. Mantovani, V. Sirbu, T. A. Bass, F. Della Rovere, A. Gavazzi and D. J. Angiolillo
Platelet glycoprotein IIb/IIIa receptor inhibitors--end of an era?
Eur Heart J (2008) 29; 429-31
M. Roffi and D. Mukherjee
Cytochrome P450 2C19 polymorphism and clopidogrel after MI
Lancet (2009) 373; 1172; author reply 72-3
R. Ramaraj
Clinical follow-up in endovascular treatment for TASC C-D lesions in femoro-popliteal segment
Catheter Cardiovasc Interv (2009) 73; 701-5
M. Rabellino, T. Zander, S. Baldi, L. Garcia Nielsen, F. J. Aragon-Sanchez, I. Zerolo, R. Llorens and M. Maynar
Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular disease
Am J Cardiol (2008) 101; 1359-63
R. Qayyum, D. M. Becker, L. R. Yanek, T. F. Moy, L. C. Becker, N. Faraday and D. Vaidya
Dynamics of platelet functional recovery following a clopidogrel loading dose in healthy volunteers
Am J Cardiol (2008) 102; 790-5
M. J. Price and P. S. Teirstein
Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation
Eur Heart J (2008) 29; 992-1000
M. J. Price, S. Endemann, R. R. Gollapudi, R. Valencia, C. T. Stinis, J. P. Levisay, A. Ernst, N. S. Sawhney, R. A. Schatz and P. S. Teirstein
Economic evaluation of bivalirudin with or without glycoprotein IIb/IIIa inhibition versus heparin with routine glycoprotein IIb/IIIa inhibition for early invasive management of acute coronary syndromes
J Am Coll Cardiol (2008) 52; 1758-68
D. S. Pinto, G. W. Stone, C. Shi, E. S. Dunn, M. R. Reynolds, M. York, J. Walczak, R. H. Berezin, R. Mehran, B. T. McLaurin, D. A. Cox, E. M. Ohman, A. M. Lincoff and D. J. Cohen
Initial assessment of clinical impact of a drug interaction between clopidogrel and proton pump inhibitors
J Am Coll Cardiol (2008) 52; 1038-9; author reply 39
E. Pezalla, D. Day and I. Pulliadath
The role of fondaparinux as an adjunct to thrombolytic therapy in acute myocardial infarction: a subgroup analysis of the OASIS-6 trial
Eur Heart J (2008) 29; 324-31
R. J. Peters, C. Joyner, J. P. Bassand, R. Afzal, S. Chrolavicius, S. R. Mehta, J. Oldgren, L. Wallentin, A. Budaj, K. A. Fox and S. Yusuf
Point-of-care measurement of clopidogrel responsiveness predicts clinical outcome in patients undergoing percutaneous coronary intervention results of the ARMYDA-PRO (Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty-Platelet Reactivity Predicts Outcome) study
J Am Coll Cardiol (2008) 52; 1128-33
G. Patti, A. Nusca, F. Mangiacapra, L. Gatto, A. D'Ambrosio and G. Di Sciascio
Prasugrel versus clopidogrel
N Engl J Med (2008) 358; 1298-9; author reply 99-301
V. Pasceri, G. Patti and G. Di Sciascio
Long-term effectiveness of early administration of glycoprotein IIb/IIIa agents to real-world patients undergoing primary percutaneous interventions: results of a registry study in an ST-elevation myocardial infarction network
Eur Heart J (2009) 30; 33-43
P. Ortolani, A. Marzocchi, C. Marrozzini, T. Palmerini, F. Saia, N. Taglieri, F. Baldazzi, G. Dall'Ara, P. Nardini, S. Gianstefani, P. Guastaroba, R. Grilli and A. Branzi
Effects of fondaparinux in patients with ST-segment elevation acute myocardial infarction not receiving reperfusion treatment
Eur Heart J (2008) 29; 315-23
. Oldgren, L. Wallentin, R. Afzal, J. P. Bassand, A. Budaj, S. Chrolavicius, K. A. Fox, C. B. Granger, S. R. Mehta, P. Pais, R. J. Peters, D. Xavier, J. Zhu and S. Yusuf
Xa inhibition and coagulation activity--the influence of prolonged dalteparin treatment and gender in patients with acute coronary syndrome and healthy individuals
Am Heart J (2008) 155; 493 e1-8
. Oldgren, N. Johnston and A. Siegbahn
Clopidogrel treatment and the MEND-CABG II trial
JAMA (2008) 300; 1021; author reply 21-2
J. Oh, N. Hong and S. M. Kang
Association between baseline neutrophil count, clopidogrel therapy, and clinical and angiographic outcomes in patients with ST-elevation myocardial infarction receiving fibrinolytic therapy
Eur Heart J (2008) 29; 984-91
M. O'Donoghue, D. A. Morrow, C. P. Cannon, W. Guo, S. A. Murphy, C. M. Gibson and M. S. Sabatine
Impact of kidney disease and blood pressure on the development of cardiovascular disease: an overview from the Japan Arteriosclerosis Longitudinal Study
Circulation (2008) 118; 2694-701
T. Ninomiya, Y. Kiyohara, Y. Tokuda, Y. Doi, H. Arima, A. Harada, Y. Ohashi and H. Ueshima
One-year clinical outcomes with abciximab vs. placebo in patients with non-ST-segment elevation acute coronary syndromes undergoing percutaneous coronary intervention after pre-treatment with clopidogrel: results of the ISAR-REACT 2 randomized trial
Eur Heart J (2008) 29; 455-61
G. Ndrepepa, A. Kastrati, J. Mehilli, F. J. Neumann, J. ten Berg, O. Bruskina, F. Dotzer, M. Seyfarth, J. Pache, J. Dirschinger, P. B. Berger and A. Schomig
Optimal treatment of renal artery in-stent restenosis: repeat stent placement versus angioplasty alone
Catheter Cardiovasc Interv (2008) 71; 701-5
Z. M. N'Dandu, R. A. Badawi, C. J. White, M. A. Grise, J. P. Reilly, J. S. Jenkins, T. J. Collins and S. R. Ramee
A thrombus stuck in the ostium of the coronary artery
Eur Heart J (2009) 30; 24
T. Nakahara, M. Manita and M. Kurabayashi
Transglutaminase activity in acute infarcts predicts healing outcome and left ventricular remodelling: implications for FXIII therapy and antithrombin use in myocardial infarction
Eur Heart J (2008) 29; 445-54
M. Nahrendorf, E. Aikawa, J. L. Figueiredo, L. Stangenberg, S. W. van den Borne, W. M. Blankesteijn, D. E. Sosnovik, F. A. Jaffer, C. H. Tung and R. Weissleder
Reduction in recurrent cardiovascular events with prasugrel compared with clopidogrel in patients with acute coronary syndromes from the TRITON-TIMI 38 trial
Eur Heart J (2008) 29; 2473-9
S. A. Murphy, E. M. Antman, S. D. Wiviott, G. Weerakkody, G. Morocutti, K. Huber, J. Lopez-Sendon, C. H. McCabe and E. Braunwald
Antithrombotic therapy to support primary PCI
N Engl J Med (2008) 358; 2280-2
D. A. Morrow
Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial
Lancet (2009) 373; 723-31
G. Montalescot, S. D. Wiviott, E. Braunwald, S. A. Murphy, C. M. Gibson, C. H. McCabe and E. M. Antman
Impact of anticoagulation levels on outcomes in patients undergoing elective percutaneous coronary intervention: insights from the STEEPLE trial
Eur Heart J (2008) 29; 462-71
G. Montalescot, M. Cohen, G. Salette, W. J. Desmet, C. Macaya, P. E. Aylward, P. G. Steg, H. D. White, R. Gallo and S. R. Steinhubl
Mechanical reperfusion: treat well, treat on time too
Lancet (2008) 372; 509-10
G. Montalescot
Cytochrome P450 2C19 polymorphism and clopidogrel after MI
Lancet (2009) 373; 1171-2; author reply 72-3
J. Miao, R. Liu and Z. Li
Unfractionated heparin dosing and risk of major bleeding in non-ST-segment elevation acute coronary syndromes
Am Heart J (2008) 156; 209-15
C. Melloni, K. P. Alexander, A. Y. Chen, L. K. Newby, M. T. Roe, N. M. Allen LaPointe, C. V. Pollack, Jr., W. B. Gibler, E. M. Ohman and E. D. Peterson
Transient ST-elevation myocardial infarction: clinical course with intense medical therapy and early invasive approach, and comparison with persistent ST-elevation myocardial infarction
Am Heart J (2008) 155; 848-54
S. R. Meisel, Y. Dagan, D. S. Blondheim, S. Dacca, M. Shochat, M. Kazatsker, A. Asif, A. Frimerman and A. Shotan
Antithrombotic therapy with fondaparinux in relation to interventional management strategy in patients with ST- and non-ST-segment elevation acute coronary syndromes: an individual patient-level combined analysis of the Fifth and Sixth Organization to Assess Strategies in Ischemic Syndromes (OASIS 5 and 6) randomized trials
Circulation (2008) 118; 2038-46
S. R. Mehta, W. E. Boden, J. W. Eikelboom, M. Flather, P. G. Steg, A. Avezum, R. Afzal, L. S. Piegas, D. P. Faxon, P. Widimsky, A. Budaj, S. Chrolavicius, H. J. Rupprecht, S. Jolly, C. B. Granger, K. A. Fox, J. P. Bassand and S. Yusuf
The Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction (HORIZONS-AMI) Trial: study design and rationale
Am Heart J (2008) 156; 44-56
. Mehran, B. Brodie, D. A. Cox, C. L. Grines, B. Rutherford, D. L. Bhatt, G. Dangas, F. Feit, E. M. Ohman, H. Parise, M. Fahy, A. J. Lansky and G. W. Stone
Abciximab in Patients With Acute ST-Segment-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention After Clopidogrel Loading. A Randomized Double-Blind Trial
Circulation (2009)
J. Mehilli, A. Kastrati, S. Schulz, S. Frungel, S. G. Nekolla, W. Moshage, F. Dotzer, K. Huber, J. Pache, J. Dirschinger, M. Seyfarth, S. Martinoff, M. Schwaiger and A. Schomig
Cytochrome p-450 polymorphisms and response to clopidogrel
N Engl J Med (2009) 360; 354-62
J. L. Mega, S. L. Close, S. D. Wiviott, L. Shen, R. D. Hockett, J. T. Brandt, J. R. Walker, E. M. Antman, W. Macias, E. Braunwald and M. S. Sabatine
Cytochrome p-450 polymorphisms and response to clopidogrel
N Engl J Med (2009) 360; 354-62
J. L. Mega, S. L. Close, S. D. Wiviott, L. Shen, R. D. Hockett, J. T. Brandt, J. R. Walker, E. M. Antman, W. Macias, E. Braunwald and M. S. Sabatine
Effectiveness of reloading to overcome clopidogrel nonresponsiveness in patients with acute myocardial infarction
Am J Cardiol (2008) 102; 524-9
S. Matetzky, P. Fefer, B. Shenkman, D. Varon, N. Savion and H. Hod
Randomized comparison between tirofiban and abciximab to promote complete ST-resolution in primary angioplasty: results of the facilitated angioplasty with tirofiban or abciximab (FATA) in ST-elevation myocardial infarction trial
Eur Heart J (2008) 29; 2972-80
A. Marzocchi, A. Manari, G. Piovaccari, C. Marrozzini, S. Marra, P. Magnavacchi, P. Sangiorgio, L. Marinucci, N. Taglieri, G. Gordini, N. Binetti, V. Guiducci, N. Franco, M. L. Reggiani and F. Saia
Long-term mortality after bolus-only administration of abciximab, eptifibatide, or tirofiban during percutaneous coronary intervention
Catheter Cardiovasc Interv (2009) 73; 214-21
. D. Marmur, S. Poludasu, J. Lazar and E. Cavusoglu
Ethnic variation in adverse cardiovascular outcomes and bleeding complications in the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) study
Am Heart J (2009) 157; 658-65
K. H. Mak, D. L. Bhatt, M. Shao, G. J. Hankey, J. D. Easton, K. A. Fox and E. J. Topol
Noncardiac Surgery and Antiplatelet Therapy Following Coronary Artery Stenting
Heart (2009)
M. J. Luckie, R. S. Khattar and D. G. Fraser
Comparison of different methods of measurement of aspirin resistance: using the appropriate statistic
Eur Heart J (2008) 29; 138; author reply 38-9
M. Lotrionte, G. G. Biondi-Zoccai, P. Agostoni and I. Sheiban
Outcomes in elderly patients with acute coronary syndromes randomized to enoxaparin vs. unfractionated heparin: results from the SYNERGY trial
Eur Heart J (2008) 29; 1827-33
. D. Lopes, K. P. Alexander, G. Marcucci, H. D. White, S. Spinler, J. Col, P. E. Aylward, R. M. Califf and K. W. Mahaffey
Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial
J Am Coll Cardiol (2009) 53; 1021-30
R. D. Lopes, K. P. Alexander, S. V. Manoukian, M. E. Bertrand, F. Feit, H. D. White, C. V. Pollack, Jr., J. Hoekstra, B. J. Gersh, G. W. Stone and E. M. Ohman
Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study
Circulation (2009) 119; 37-43
W. Lieb, M. G. Larson, E. J. Benjamin, X. Yin, G. H. Tofler, J. Selhub, P. F. Jacques, T. J. Wang, J. A. Vita, D. Levy, R. S. Vasan and G. F. Mitchell
Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study
Circulation (2009) 119; 37-43
W. Lieb, M. G. Larson, E. J. Benjamin, X. Yin, G. H. Tofler, J. Selhub, P. F. Jacques, T. J. Wang, J. A. Vita, D. Levy, R. S. Vasan and G. F. Mitchell
Dosing of clopidogrel for platelet inhibition in infants and young children: primary results of the Platelet Inhibition in Children On cLOpidogrel (PICOLO) trial
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J. S. Li, E. Yow, K. Y. Berezny, P. M. Bokesch, M. Takahashi, T. P. Graham, Jr., S. P. Sanders, D. Sidi, D. Bonnet, P. Ewert, L. K. Jennings and A. D. Michelson
Effect of clopidogrel pretreatment on angiographic and clinical outcomes in patients undergoing primary percutaneous coronary intervention for ST-elevation acute myocardial infarction
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E. I. Lev, R. Kornowski, H. Vaknin-Assa, D. Brosh, S. Fuchs, A. Battler and A. Assali
Smoking status and antithrombin therapy in patients with non-ST-segment elevation acute coronary syndrome
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S. Leung, D. Gallup, K. W. Mahaffey, M. Cohen, E. M. Antman, S. G. Goodman, R. A. Harrington, A. Langer, P. Aylward, J. J. Ferguson and R. M. Califf
Impact of high loading and maintenance dose of clopidogrel within the first 15 days after percutaneous coronary intervention on patient outcome
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G. Lemesle, C. Delhaye, A. Sudre, D. Broucqsault, G. Rosey, C. Bauters and J. M. Lablanche
Impact of bivalirudin on in-hospital bleeding and six-month outcomes in octogenarians undergoing percutaneous coronary intervention
Catheter Cardiovasc Interv (2009)
G. Lemesle, A. De Labriolle, L. Bonello, A. Syed, S. Collins, G. Maluenda, R. Torguson, K. Kaneshige, Z. Xue, W. O. Suddath, L. F. Satler, K. M. Kent, J. Lindsay, A. D. Pichard and R. Waksman
Comparison between ticlopidine and clopidogrel in patients undergoing primary stenting in acute myocardial infarction: results from the CADILLAC trial
Catheter Cardiovasc Interv (2008) 72; 917-24
A. J. Lansky, Y. Tsuchiya, M. Brener, R. Mehran, E. Cristea, C. Pietras, C. L. Grines, D. A. Cox, E. Garcia, J. E. Tcheng, G. Guagliumi, T. Stuckey, M. Turco, J. D. Carroll, B. D. Rutherford, M. B. Leon, J. Moses and G. W. Stone
Clopidogrel 600-mg double loading dose achieves stronger platelet inhibition than conventional regimens: results from the PREPAIR randomized study
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P. L. L'Allier, G. Ducrocq, N. Pranno, S. Noble, R. Ibrahim, J. C. Gregoire, F. Azzari, A. Nozza, C. Berry, S. Doucet, B. Labarthe, P. Theroux and J. C. Tardif
Interindividual variability in the response to oral antiplatelet drugs: a position paper of the Working Group on antiplatelet drugs resistance appointed by the Section of Cardiovascular Interventions of the Polish Cardiac Society, endorsed by the Working Group on Thrombosis of the European Society of Cardiology
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W. Kuliczkowski, A. Witkowski, L. Polonski, C. Watala, K. Filipiak, A. Budaj, J. Golanski, D. Sitkiewicz, J. Pregowski, J. Gorski, M. Zembala, G. Opolski, K. Huber, H. Arnesen, S. D. Kristensen and R. De Caterina
The problem with composite end points in cardiovascular studies: the story of major adverse cardiac events and percutaneous coronary intervention
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K. E. Kip, K. Hollabaugh, O. C. Marroquin and D. O. Williams
Comparison of coronary flow reserve and fractional flow reserve in patients with versus without diabetes mellitus and having elective percutaneous coronary intervention and abciximab therapy (from the PREDICT Trial)
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A. S. Kini, M. C. Kim, P. R. Moreno, P. Krishnan, O. C. Ivan and S. K. Sharma
Bolus-only versus bolus + infusion of glycoprotein IIb/IIIa inhibitors during percutaneous coronary intervention
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A. S. Kini, V. H. Chen, P. Krishnan, P. Lee, M. C. Kim, A. Mares, J. Suleman, P. R. Moreno and S. K. Sharma
Clopidogrel use and bleeding after coronary artery bypass graft surgery
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Adverse events associated with stopping clopidogrel after acute coronary syndrome
JAMA (2008) 299; 2388-9; author reply 89-90
D. H. Kim
Bivalirudin versus unfractionated heparin during percutaneous coronary intervention
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Safety of percutaneous coronary intervention during uninterrupted oral anticoagulant treatment
Eur Heart J (2008) 29; 1001-10
P. P. Karjalainen, S. Vikman, M. Niemela, P. Porela, A. Ylitalo, M. A. Vaittinen, M. Puurunen, T. J. Airaksinen, K. Nyman, T. Vahlberg and K. E. Airaksinen
Thrombogenicity in patients with percutaneous coronary artery intervention and dual antiplatelet treatment
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P. W. Kamphuisen
Fondaparinux compared to enoxaparin in patients with acute coronary syndromes without ST-segment elevation: outcomes and treatment effect across different levels of risk
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C. D. Joyner, R. J. Peters, R. Afzal, S. Chrolavicius, S. R. Mehta, K. A. Fox, C. B. Granger, M. G. Franzosi, M. Flather, A. Budaj, J. P. Bassand and S. Yusuf
Effects of aspirin dose on ischaemic events and bleeding after percutaneous coronary intervention: insights from the PCI-CURE study
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S. S. Jolly, J. Pogue, K. Haladyn, R. J. Peters, K. A. Fox, A. Avezum, B. J. Gersh, H. J. Rupprecht, S. Yusuf and S. R. Mehta
Outcomes associated with combined antiplatelet and anticoagulant therapy
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S. G. Johnson, K. Rogers, T. Delate and D. M. Witt
Randomized comparison of adjunctive cilostazol versus high maintenance dose clopidogrel in patients with high post-treatment platelet reactivity: results of the ACCEL-RESISTANCE (Adjunctive Cilostazol Versus High Maintenance Dose Clopidogrel in Patients With Clopidogrel Resistance) randomized study
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Y. H. Jeong, S. W. Lee, B. R. Choi, I. S. Kim, M. K. Seo, C. H. Kwak, J. Y. Hwang and S. W. Park
Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) trial
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S. James, A. Akerblom, C. P. Cannon, H. Emanuelsson, S. Husted, H. Katus, A. Skene, P. G. Steg, R. F. Storey, R. Harrington, R. Becker and L. Wallentin
Chronically anticoagulated patients who need surgery: Can low-molecular-weight heparins really be used to "bridge" patients instead of intravenous unfractionated heparin?
Catheter Cardiovasc Interv (2009)
M. R. Jaff
Cardiovascular outcomes after a change in prescription policy for clopidogrel
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Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome
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P. M. Ho, T. M. Maddox, L. Wang, S. D. Fihn, R. L. Jesse, E. D. Peterson and J. S. Rumsfeld
Should we monitor platelet function during antiplatelet therapy?
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P. Hjemdahl
Cilostazol in addition to aspirin and clopidogrel improves long-term outcomes after percutaneous coronary intervention in patients with acute coronary syndromes: a randomized, controlled study
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Y. Han, Y. Li, S. Wang, Q. Jing, Z. Wang, D. Wang, Q. Shu and X. Tang
The relative safety and efficacy of abciximab and eptifibatide in patients undergoing primary percutaneous coronary intervention: insights from a large regional registry of contemporary percutaneous coronary intervention
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H. S. Gurm, D. E. Smith, J. S. Collins, D. Share, A. Riba, A. J. Carter, T. LaLonde, E. Kline-Rogers, M. O'Donnell, H. Changezi, M. Zughaib, R. Safian and M. Moscucci
Bivalirudin and clopidogrel with and without eptifibatide for elective stenting: effects on platelet function, thrombelastographic indexes, and their relation to periprocedural infarction results of the CLEAR PLATELETS-2 (Clopidogrel with Eptifibatide to Arrest the Reactivity of Platelets) study
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P. A. Gurbel, K. P. Bliden, J. F. Saucedo, T. A. Suarez, J. DiChiara, M. J. Antonino, E. Mahla, A. Singla, W. R. Herzog, A. K. Bassi, T. A. Hennebry, T. B. Gesheff and U. S. Tantry
Adverse events associated with stopping clopidogrel after acute coronary syndrome
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Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents
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Early versus Delayed, Provisional Eptifibatide in Acute Coronary Syndromes
N Engl J Med (2009)
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Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study
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M. Gilard, B. Arnaud, J. C. Cornily, G. Le Gal, K. Lacut, G. Le Calvez, J. Mansourati, D. Mottier, J. F. Abgrall and J. Boschat
Ensuring appropriate use of antiplatelet agents in the treatment of acute coronary syndromes--have cardiovascular physicians been given enough grace in getting it right?
Heart (2008) 94; 135-7
A. H. Gershlick
Residual platelet activity is increased in clopidogrel- and ASA-treated patients with coronary stenting for acute coronary syndromes compared with stable coronary artery disease
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Abbreviated infusion of eptifibatide after successful coronary intervention The BRIEF-PCI (Brief Infusion of Eptifibatide Following Percutaneous Coronary Intervention) randomized trial
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Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: a report from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial
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F. Feit, S. V. Manoukian, R. Ebrahimi, C. V. Pollack, E. M. Ohman, M. J. Attubato, R. Mehran and G. W. Stone
Guidelines for anticoagulant use in acute coronary syndromes
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J. Eikelboom, G. Guyatt and J. Hirsh
Comparison of increased aspirin dose versus combined aspirin plus clopidogrel therapy in patients with diabetes mellitus and coronary heart disease and impaired antiplatelet response to low-dose aspirin
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M. A. Duzenli, K. Ozdemir, N. Aygul, A. Soylu and M. Tokac
Interaction between cigarette smoking and clinical benefit of clopidogrel
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N. R. Desai, J. L. Mega, S. Jiang, C. P. Cannon and M. S. Sabatine
Early glycoprotein IIb-IIIa inhibitors in primary angioplasty (EGYPT) cooperation: an individuEarly glycoprotein IIb-IIIa inhibitors in primary angioplasty (EGYPT) cooperation: an individual patient data meta-analysis al patient data meta-analysis
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Outcomes with the use of glycoprotein IIb/IIIa inhibitors in non-ST-segment elevation acute coronary syndromes
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Relation of low response to clopidogrel assessed with point-of-care assay to periprocedural myonecrosis in patients undergoing elective coronary stenting for stable angina pectoris
Am J Cardiol (2008) 101; 1700-3
T. Cuisset, M. Hamilos, J. Sarma, G. Sarno, E. Wyffels, M. Vanderheyden, E. Barbato, J. Bartunek, B. De Bruyne and W. Wijns
Adjusting clopidogrel loading doses according to vasodilator-stimulated phosphoprotein index: on time, too early, or too late?
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T. Cuisset, C. Frere, J. Quilici, M. C. Alessi and J. L. Bonnet
Dose effect of clopidogrel reloading in patients already on 75-mg maintenance dose: the Reload with Clopidogrel Before Coronary Angioplasty in Subjects Treated Long Term with Dual Antiplatelet Therapy (RELOAD) study
Circulation (2008) 118; 1225-33
J. P. Collet, J. Silvain, A. Landivier, M. L. Tanguy, G. Cayla, A. Bellemain, N. Vignolles, S. Gallier, F. Beygui, A. Pena and G. Montalescot
Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study
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J. P. Collet, J. S. Hulot, A. Pena, E. Villard, J. B. Esteve, J. Silvain, L. Payot, D. Brugier, G. Cayla, F. Beygui, G. Bensimon, C. Funck-Brentano and G. Montalescot
Emerging transcatheter therapies for aortic and mitral disease
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R. D. Christofferson, S. R. Kapadia, V. Rajagopal and E. M. Tuzcu
Patients with non-ST-elevation acute coronary syndromes undergoing coronary artery bypass grafting in the modern era of antithrombotic therapy
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Predictors of initial nontherapeutic anticoagulation with unfractionated heparin in ST-segment elevation myocardial infarction
Circulation (2009) 119; 1195-202
S. Cheng, D. A. Morrow, S. Sloan, E. M. Antman and M. S. Sabatine
What anti-thrombotic therapy is best with primary PCI for acute ST elevation myocardial infarction: how should the HORIZONS trial change current practice?
Catheter Cardiovasc Interv (2008) 71; 816-21
B. R. Brodie
Long-term outcomes by clopidogrel duration and stent type in a diabetic population with de novo coronary artery lesions
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S. S. Brar, J. Kim, S. K. Brar, R. Zadegan, M. Ree, I. L. Liu, P. Mansukhani, V. Aharonian, R. Hyett and A. Y. Shen
Impact of a 600-mg loading dose of clopidogrel on 30-day outcome in unselected patients undergoing percutaneous coronary intervention
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L. Bonello, G. Lemesle, A. De Labriolle, P. Roy, D. H. Steinberg, T. L. Pinto Slottow, Z. Xue, R. Torguson, W. O. Suddath, L. F. Satler, K. M. Kent, A. D. Pichard, J. Lindsay and R. Waksman
Emergence of the Concept of Platelet Reactivity Monitoring of Response to Thienopyridines
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L. Bonello, A. De Labriolle, M. Scheinowitz, G. Lemesle, P. Roy, D. H. Steinberg, T. L. Pinto Slottow, R. Pakala, A. D. Pichard, P. Barragan, L. Camoin-Jau, F. Dignat-George, F. Paganelli and R. Waksman
Bivalirudin with provisional glycoprotein IIb/IIIa inhibitors in patients undergoing primary angioplasty in the setting of cardiogenic shock
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L. Bonello, A. De Labriolle, P. Roy, D. H. Steinberg, T. L. Pinto Slottow, Z. Xue, K. Smith, R. Torguson, W. O. Suddath, L. F. Satler, K. M. Kent, A. D. Pichard and R. Waksman
Prognosis of patients suffering an acute coronary syndrome while already under chronic clopidogrel therapy
Catheter Cardiovasc Interv (2008)
L. Bonello, A. De Labriolle, G. Lemesle, D. H. Steinberg, P. Roy, R. Torguson, W. O. Suddath, L. F. Satler, K. M. Kent, A. D. Pichard and R. Waksman
Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: a multicenter randomized prospective study
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L. Bonello, L. Camoin-Jau, S. Arques, C. Boyer, D. Panagides, O. Wittenberg, M. C. Simeoni, P. Barragan, F. Dignat-George and F. Paganelli
Tailored clopidogrel loading dose according to platelet reactivity monitoring to prevent acute and subacute stent thrombosis
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L. Bonello, L. Camoin-Jau, S. Armero, O. Com, S. Arques, C. Burignat-Bonello, M. P. Giacomoni, R. Bonello, F. Collet, P. Rossi, P. Barragan, F. Dignat-George and F. Paganelli
The association of cigarette smoking with enhanced platelet inhibition by clopidogrel
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K. P. Bliden, J. Dichiara, L. Lawal, A. Singla, M. J. Antonino, B. A. Baker, W. L. Bailey, U. S. Tantry and P. A. Gurbel
Cytochrome P450 2C19 polymorphism and clopidogrel after MI
Lancet (2009) 373; 1171; author reply 72-3
S. Bhattacharyya and R. Rakhit
The efficacy and safety of short- and long-term dual antiplatelet therapy in patients with mild or moderate chronic kidney disease: results from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial
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P. J. Best, S. R. Steinhubl, P. B. Berger, A. Dasgupta, D. M. Brennan, L. A. Szczech, R. M. Califf and E. J. Topol
Incidence, predictors, and clinical impact of bleeding after transradial coronary stenting and maximal antiplatelet therapy
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O. F. Bertrand, E. Larose, J. Rodes-Cabau, O. Gleeton, I. Taillon, L. Roy, P. Poirier, O. Costerousse and R. D. Larochelliere
Impact of clopidogrel in patients with acute coronary syndromes requiring coronary artery bypass surgery: a multicenter analysis
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J. S. Berger, C. B. Frye, Q. Harshaw, F. H. Edwards, S. R. Steinhubl and R. C. Becker
Comparison of the impact of short (<1 year) and long-term (> or =1 year) clopidogrel use following percutaneous coronary intervention on mortality
Am J Cardiol (2008) 102; 1159-62
S. Banerjee, C. Varghese, J. Samuel, R. A. Weideman, B. B. Little, K. C. Kelly, S. V. Rao, R. F. Reilly and E. S. Brilakis
Bleeding risk associated with 1 year of dual antiplatelet therapy after percutaneous coronary intervention: Insights from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial
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H. D. Aronow, S. R. Steinhubl, D. M. Brennan, P. B. Berger and E. J. Topol
Relation between aspirin dose, all-cause mortality, and bleeding in patients with recent cerebrovascular or coronary ischemic events (from the BRAVO Trial)
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H. D. Aronow, R. M. Califf, R. A. Harrington, M. Vallee, C. Graffagnino, A. Shuaib, D. J. Fitzgerald, J. D. Easton, F. Van de Werf, H. C. Diener, J. Ferguson, P. J. Koudstaal, P. Amarenco, P. Theroux, S. Davis and E. J. Topol
Optimizing clopidogrel therapy before stent implantation: should clinical setting be taken into account?
J Am Coll Cardiol (2008) 52; 1349; author reply 49-50
D. Aradi, A. Vorobcsuk and A. Komocsi
Early and late benefits of prasugrel in patients with acute coronary syndromes undergoing percutaneous coronary intervention: a TRITON-TIMI 38 (TRial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet InhibitioN with Prasugrel-Thrombolysis In Myocardial Infarction) analysis
J Am Coll Cardiol (2008) 51; 2028-33
E. M. Antman, S. D. Wiviott, S. A. Murphy, J. Voitk, Y. Hasin, P. Widimsky, H. Chandna, W. Macias, C. H. McCabe and E. Braunwald
Functional effects of high clopidogrel maintenance dosing in patients with inadequate platelet inhibition on standard dose treatment
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D. J. Angiolillo, M. A. Costa, S. B. Shoemaker, B. Desai, E. Bernardo, Y. Suzuki, R. K. Charlton, M. M. Zenni, L. A. Guzman and T. A. Bass
Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel
J Am Coll Cardiol (2008) 52; 1052-9
L. Ang, V. Palakodeti, A. Khalid, S. Tsimikas, Z. Idrees, P. Tran, P. Clopton, N. Zafar, G. Bromberg-Marin, S. Keramati and E. Mahmud
Patterns of upstream antiplatelet therapy use before primary percutaneous coronary intervention for acute ST-elevation myocardial infarction (from the CRUSADE National Quality Improvement Initiative)
Am J Cardiol (2008) 102; 1335-40
D. Alexander, N. Mann, F. S. Ou, E. D. Peterson, E. M. Ohman, W. B. Gibler and M. T. Roe
Impact of home warfarin use on the treatment and outcomes of patients undergoing percutaneous coronary intervention
Am J Cardiol (2008) 101; 1413-7
A. Aggarwal, D. Dai, J. S. Rumsfeld, L. W. Klein and M. T. Roe
Comparison of higher clopidogrel loading and maintenance dose to standard dose on platelet function and outcomes after percutaneous coronary intervention using drug-eluting stents
Am J Cardiol (2008) 102; 401-3
M. Abuzahra, M. Pillai, A. Caldera, W. B. Hartley, R. Gonzalez, J. Bobek, H. Dokainish and N. Lakkis